Mothers who consume vitamin D during pregnancy bring babies to life with certain cognitive improvements
Although it is warned that consuming too much vitamin D can be harmful, as it accumulates in the body and causes high levels of calcium
A recent clinical trial that followed nearly 500 children in Denmark showed that those whose mothers received high-dose vitamin D supplements during pregnancy showed slight improvements on tests of verbal and visual memory and cognitive flexibility at age 10. However, no differences were observed in overall intelligence scores.
This study, published in JAMA Network Open, considered a randomized controlled trial, stands out for its design that allows for the reduction of bias factors. Participants were randomly assigned to groups receiving doses of 400 or 2,400 international units of vitamin D daily.
Although the results showed statistically significant improvements, they were considered modest compared to other factors relevant to cognitive development.
Recommendations for pregnant women
Despite the findings, Dr. Leana Wen, associate professor at George Washington University and CNN wellness expert, warned in an interview with that outlet against self-prescribing high doses of vitamin D.
Notes that pregnant women should consult their obstetrician before starting any additional supplementation. The dose used in the study was considerably higher than the commonly recommended 400 units daily.
Wen explains, at the same time, that too much vitamin D can be harmful, as it accumulates in the body and causes high levels of calcium, which could cause serious side effects, such as kidney or heart damage. The importance of addressing supplementation in the context of comprehensive prenatal care is emphasized.
Measurement of cognitive effects of vitamin D in children
To evaluate the cognitive effects of vitamin D in children in future studies, it is recommended to combine measures of vitamin D status (serum 25-OH-vitamin D levels) with validated neuropsychological tests and longitudinal or intervention designs.
Measurement of vitamin D status
Assessment of cognitive function
Ethical and practical considerations
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